Bactin 5

Bactin contains Mupirocin USP, 2% w/w.  After topical application of mupirocin ointment, mupirocin is only very minimally absorbed systemically. Following topical administration, >97% of the drug is bound to protein. It is rapidly metabolised to inactive monic acid and excreted via the kidneys. The elimination half life is 20-40 minutes for mupirocin and 30-80 minutes for monic acid. Penetration of mupirocin into the deeper epidermal and dermal layers of the skin is enhanced in traumatised skin and under occlusive dressings.