- Overview
- Uses
- Benefits
- Side Effect
- How to use
- How It works
- What if you forget to take?
- Safety Advice
- FAQ
Author Details

NepMeds

Last Updated On: Jul 14, 2025
Mycofit 500mg
Rs. 0
Product Overview
Mycofit 500mg is a medication that contains the active ingredient Mycophenolate Mofetil. It is used in the field of organ transplantation as an immunosuppressive drug. Mycophenolate Mofetil is commonly prescribed to prevent rejection of transplanted organs, such as kidney, heart, or liver, by suppressing the immune system's response to the new organ. This helps to ensure that the body does not attack and reject the transplanted organ.
It is important to note that Mycofit 500mg should only be taken under the supervision and guidance of a qualified healthcare professional, as it can have various side effects and interactions with other medications. The dosage and duration of treatment will depend on the specific medical condition and the transplant recipient's individual needs. Patients should follow their doctor's instructions carefully and report any unusual or severe side effects.
Common side effects of Mycofit 500mg may include gastrointestinal symptoms like nausea, vomiting, diarrhea, and abdominal pain. It can also affect the blood cell count and increase the risk of infections. Regular monitoring of blood counts and overall health is typically required during treatment with this medication
Uses
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Immunosuppression in Organ Transplantation: Mycofit 500mg is commonly prescribed to transplant recipients as part of an immunosuppressive regimen. It helps prevent the recipient's immune system from attacking and rejecting the transplanted organ, such as a kidney, heart, liver, or lung. This is crucial to ensure the long-term success of the transplant.
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Treatment of Autoimmune Diseases: Mycophenolate Mofetil may also be used to manage certain autoimmune diseases where the immune system mistakenly attacks the body's own tissues. Conditions such as systemic lupus erythematosus (SLE), lupus nephritis, and certain types of vasculitis may be treated with this medication.
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Treatment of Severe Psoriasis: In some cases, Mycofit may be prescribed off-label for the treatment of severe psoriasis, a chronic skin condition
Benefits
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Prevention of Organ Rejection: Mycofit 500mg is a vital component of immunosuppressive therapy in organ transplantation. By suppressing the immune system's response, it reduces the risk of the recipient's body rejecting the transplanted organ, such as a kidney, heart, liver, or lung. This significantly improves the chances of long-term success for transplant recipients.
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Management of Autoimmune Diseases: In autoimmune diseases like systemic lupus erythematosus (SLE) and lupus nephritis, the immune system mistakenly attacks the body's own tissues. Mycofit can help control this immune response, reducing inflammation and symptom severity in these conditions.
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Reduction of Disease Flare-Ups: For patients with autoimmune diseases, Mycofit may help prevent or reduce the frequency and severity of disease flare-ups. This can lead to an improved quality of life and better disease management.
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Alternative to Other Immunosuppressants: Mycofit provides an alternative or adjunct to other immunosuppressive medications, allowing healthcare providers to tailor treatment regimens to the patient's specific needs and circumstances.
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Treatment of Severe Psoriasis (Off-Label): In some cases, Mycofit may be used off-label to treat severe psoriasis, a chronic skin condition. Its immunosuppressive effects can help reduce the excessive immune response that contributes to psoriasis symptoms
Side Effect
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Gastrointestinal Symptoms: These are among the most common side effects and can include nausea, vomiting, diarrhea, and abdominal pain. Taking the medication with food or dividing the daily dose into smaller, more frequent doses may help reduce these symptoms.
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Infections: Mycofit suppresses the immune system, which can increase the risk of infections. This may include respiratory, urinary tract, or other infections. It's essential to report any signs of infection to your healthcare provider promptly.
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Bone Marrow Suppression: Mycofit can affect the bone marrow's ability to produce blood cells, leading to anemia (low red blood cell count), leukopenia (low white blood cell count), and thrombocytopenia (low platelet count). Regular blood tests are typically conducted to monitor these levels.
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Increased Susceptibility to Skin Cancer: Long-term use of Mycofit may increase the risk of developing skin cancer, particularly in patients with a history of high sun exposure. Sun protection measures, such as sunscreen and protective clothing, are recommended.
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Liver Function Abnormalities: Mycofit can affect liver function, leading to elevated liver enzymes. Regular liver function tests are typically conducted to monitor for any issues.
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Nervous System and Mood Changes: Some individuals may experience headaches, dizziness, or mood changes while taking Mycofit.
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Respiratory Symptoms: Coughing and difficulty breathing have been reported in some cases.
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Gastrointestinal Bleeding: Rarely, Mycofit may lead to gastrointestinal bleeding, which can present as dark, tarry stools or vomiting blood.
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Hypertension (High Blood Pressure): Elevated blood pressure may occur in some individuals.
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Birth Defects: Mycofit should not be used during pregnancy, as it can cause birth defects. Effective contraception should be used during treatment, and pregnancy should be avoided
How to use
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Dosage: The dosage of Mycofit 500mg can vary depending on the type of organ transplant or medical condition being treated. Your healthcare provider will determine the appropriate dose for you.
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Frequency: Mycofit is usually taken twice a day, approximately 12 hours apart. Follow your healthcare provider's specific instructions regarding the dosing schedule.
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Administration: Mycofit tablets should be swallowed whole with a full glass of water. Do not crush, chew, or break the tablets unless your healthcare provider instructs you to do so.
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Timing: It's important to take Mycofit consistently at the same times each day to maintain a steady level of the medication in your bloodstream. This helps ensure its effectiveness.
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Food Interaction: To reduce the likelihood of gastrointestinal side effects like nausea and vomiting, you can take Mycofit with food. Taking it with a meal or a light snack may help minimize these symptoms.
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Avoid Alcohol: It's advisable to avoid alcohol while taking Mycofit, as it can increase the risk of certain side effects and interactions.
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Contraception: If you are of childbearing potential and sexually active, you should use effective contraception methods while taking Mycofit, as this medication can cause birth defects. Discuss contraceptive options with your healthcare provider.
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Regular Monitoring: Your healthcare provider will schedule regular blood tests to monitor your blood cell counts, kidney function, liver function, and overall health during Mycofit treatment. This monitoring helps detect and manage potential side effects or complications.
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Follow Instructions: Always follow your healthcare provider's instructions regarding dosage adjustments, possible changes in medication, and any precautions or special considerations specific to your condition.
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Do Not Stop Abruptly: It's important not to stop taking Mycofit suddenly or change the dosage without consulting your healthcare provider. Abrupt discontinuation can increase the risk of organ rejection or exacerbate autoimmune disease symptoms.
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Communicate with Your Healthcare Provider: If you experience any unusual or severe side effects, have questions about your medication, or need to make any changes to your treatment plan, contact your healthcare provider promptly
How It works
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Inhibition of DNA Synthesis: Mycophenolate Mofetil primarily works by inhibiting the synthesis of DNA in rapidly dividing immune cells, particularly lymphocytes (a type of white blood cell). Lymphocytes are a key component of the immune system and play a crucial role in recognizing and attacking foreign substances, including transplanted organs or the body's own tissues in autoimmune diseases.
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Targeting T and B Lymphocytes: Mycophenolate Mofetil specifically targets T and B lymphocytes, which are responsible for initiating immune responses. These cells are involved in the production of antibodies and the coordination of immune reactions. By inhibiting their DNA synthesis, the drug reduces their ability to multiply and function effectively.
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Immune System Suppression: With reduced T and B cell activity, the overall immune response is dampened. This suppression is essential in organ transplantation because it prevents the immune system from recognizing the transplanted organ as foreign and mounting an attack (rejection). In autoimmune diseases, it helps to control the immune system's overactive response against the body's own tissues.
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Selective Action: Importantly, Mycophenolate Mofetil has a selective action on immune cells, primarily affecting those that are actively dividing. This allows for a degree of specificity in targeting the immune response without completely shutting down the immune system. Other cells in the body, which do not rely on rapid DNA synthesis, are less affected.
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Maintenance Therapy: Mycophenolate Mofetil is typically used as a long-term maintenance therapy to provide ongoing immune suppression. It is often part of a combination therapy with other immunosuppressive medications to achieve the desired level of immune control while minimizing side effects.
What if you forget to take?
Try to take the missed dose as soon as possible, but if it's close to the time for your next scheduled dose, skip the missed dose entirely. Do not double up on doses to make up for the missed one.
Safety Advice for Mycofit 500mg
Alcohol and Smoking
: Limit or avoid alcohol consumption while taking Mycofit, as it can interact with the medication and increase the risk of certain side effects. Smoking can also have adverse effects on your health, so quitting is advisable.
Frequently Asked Questions
What is Mycofit 500mg used for?
Mycofit 500mg is primarily used in organ transplantation to prevent rejection of transplanted organs. It can also be used to manage certain autoimmune diseases.
How does Mycofit work?
Mycofit works by suppressing the activity of the immune system, specifically T and B lymphocytes, which are responsible for immune responses. This helps prevent the immune system from attacking transplanted organs or damaging healthy tissues in autoimmune diseases. .
What should I do if I forget to take Mycofit?
If you forget a dose, take it as soon as you remember. If it's close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double up on doses.
Can I drink alcohol while taking Mycofit?
It's advisable to limit or avoid alcohol while taking Mycofit, as alcohol can interact with the medication and increase the risk of certain side effects.