- Overview
- Uses
- Benefits
- Side Effect
- How to use
- How It works
- What if you forget to take?
- Safety Advice
- FAQ
Author Details
NepMeds
Last Updated On: Jan 21, 2025
Durataz-4.5 Inj
Rs. 0
Product Overview
Composition: Piperacillin (4000 mg) + Tazobactam (500 mg)
Durataz 4.5 g Injection is a combination of Piperacillin and Tazobactam. It is used for the treatment of bacterial infections that affect the lungs, urinary tract, skin, etc. This medication is effective only for the treatment of infections caused by bacteria and not viruses. Durataz 4.5 g Injection is effective against a large number of bacteria. Piperacillin works by preventing the formation of bacterial cell walls and killing the infection-causing bacteria. Tazobactam protects Piperacillin and ensures extended anti-bacterial activity.
Durataz 4.5 g Injection is not recommended if you are allergic to it. This medicine is not advisable for children below 2 years of age. Inform your doctor if you have any kidney/liver problems or a history of seizures (fits) before starting treatment with this medicine. Consult your doctor if you are pregnant or are breastfeeding.
Uses
- Community acquired pneumonia
- Nosocomial Pneumonia or Hospital-acquired Pneumonia (HAP)
- Urinary Tract Infection
- Intra abdominal infection
- Skin and Skin Structure Infection
- Bacterial Septicaemia
Side Effect
Common side effects:
- Diarrhoea
- Headache
- Sleeplessness
- Abdominal pain
- Nausea and Vomiting
- Stomach upset
- Skin rash and itching
- Fever
- Injection site reactions (redness, pain, swelling)
- Joint and muscle pain
How to use
DURATAZ 4.5GM INJECTION will be administered into the vein (intravenously) by your doctor or nurse. Your doctor will administer the correct dose and duration for you depending upon your age, body weight and disease condition.
How It works
DURATAZ 4.5GM INJECTION works by destroying the bacterial growth responsible for causing infections. Piperacillin works by interrupting the cell wall formation by binding with the enzymes responsible for cell wall synthesis. This binding causes defects in the cell wall leading to cell death causing death of the organism. Tazobactam is responsible for the irreversible termination of enzymes (beta- lactamases) that protect the organism from antibiotics and produces less anti-bacterial actions when given alone so it’s always used in combination with other antibiotics. Thus, both the substances works by preventing cell growth and function inhibiting bacterial growth.
Safety Advice for Durataz-4.5 Inj
Alcohol
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption
Pregnancy
Due to a lack of safety and efficacy studies in pregnant women, the risk to your developing foetus is not known. If you are pregnant, take Durataz 4.5 g Injection only if prescribed by your doctor.
Breastfeeding
Durataz 4.5 g Injection passes into breast milk in very low quantities and may cause diarrhoea in your breastfed infant. If you are breastfeeding, consult your doctor.
Frequently Asked Questions